Keywords
How to Cite
Abstract
Ushbu maqolada mitoxondriyaning tuzilishi, funksiyasi, kelib chiqishi va inson hayotidagi ahamiyati keng yoritiladi. Mitoxondriya “hujayraning energiya markazi” sifatida tanilgan bo‘lib, u adenosin trifosfat (ATF) ishlab chiqarish orqali hujayraning barcha biologik jarayonlarini ta’minlaydi. Maqolada mitoxondriyalarning ikki qavatli membranasi, o‘z DNKsiga ega bo‘lishi, energiya almashinuvidagi roli, shuningdek, mitoxondrial kasalliklar va qarish jarayonidagi ishtiroki tahlil qilinadi. Shuningdek, zamonaviy ilm-fan nuqtayi nazaridan mitoxondriyaning evolyutsion kelib chiqishi va uning genetik mustaqilligi haqidagi nazariyalar ham muhokama qilinadi.
References
1.Alberts, B., Johnson, A., Lewis, J., et al. (2019). Molecular Biology of the Cell. 7th Edition. New York: Garland Science.
2.Margulis, L. (1970). Origin of Eukaryotic Cells. Yale University Press.
3.Wallace, D. C. (2015). “Mitochondrial DNA variation in human radiation and disease.” Cell, 163(1): 33–38.
4.Nunnari, J., & Suomalainen, A. (2012). “Mitochondria: in sickness and in health.” Cell, 148(6): 1145–1159.
5.Murphy, M. P. (2009). “How mitochondria produce reactive oxygen species.” Biochemical Journal, 417(1): 1–13.
6.Lane, N. (2005). Power, Sex, Suicide: Mitochondria and the Meaning of Life. Oxford University Press.
7.Picard, M., & Wallace, D. C. (2020). “The aging mitochondria.” Physiology Reviews, 100(2): 595–651.
8.Gorman, G. S. et al. (2016). “Mitochondrial diseases.” Nature Reviews Disease Primers, 2(1): 16080.
9.Friedman, J. R., & Nunnari, J. (2014). “Mitochondrial form and function.” Nature, 505: 335–343.
10.Trifunovic, A., & Larsson, N.-G. (2008). “Mitochondrial dysfunction as a cause of ageing.” Journal of Internal Medicine, 263(2): 167–178.
11.Chinnery, P. F., & Hudson, G. (2013). “Mitochondrial genetics.” British Medical Bulletin, 106(1): 135–159.
12.Tanaka, M., & Ozawa, T. (1994). “Genetic disorders of human mitochondrial DNA.” Japanese Journal of Human Genetics, 39: 13–22.
13.OpenAI Biolabs (2024). Modern mitochondrial therapies and bioenergetics. Online Scientific
This work is licensed under a Creative Commons Attribution 4.0 International License.
