ISSN 3060-4745 Open Access · Peer Reviewed
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Keywords

lung gangrene
destructive pneumonia
necrotic pneumonia
anaerobic infection
sepsis
computed tomography
bronchial drainage
thoracic surgery
antibiotic therapy

How to Cite

Lung Gangrene: Etiology, Clinical Course, Diagnosis, and Treatment Approaches. (2026). ACUMEN: INTERNATIONAL JOURNAL OF MULTIDISCIPLINARY RESEARCH, 3(5), 1200-1208. https://doi.org/10.66301/c1rb1734

Abstract

Lung gangrene is a life-threatening destructive pulmonary disease characterized by unrestricted purulent-necrotic destruction of the lung parenchyma. It often develops against a background of severe pneumonia, aspiration, anaerobic microflora, impaired bronchial drainage, decreased immunity, sepsis, or acute disruption of pulmonary circulation. Results indicate that early diagnosis, contrast-enhanced computed tomography, microbiological evaluation, comprehensive antibacterial therapy, correction of respiratory failure, and surgical intervention in necessary cases are crucial in lung gangrene. The article is prepared for educational and scientific purposes and cannot replace individual medical advice or independent treatment guidelines.
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References

1. Arslonov Y., Nazarov T. Ichki kasalliklar. Tibbiyot kollejlari va oliy ta’lim muassasalari uchun o‘quv adabiyoti. Toshkent: O‘zbekiston tibbiy nashrlari.

2. Ubaydullayeva N. N., Ubaydullayev A. M., Tashmetova G. T. Pulmonologiya bo‘yicha o‘quv dasturi va klinik-amaliy materiallar. Toshkent: Tibbiyot xodimlarining kasbiy malakasini rivojlantirish markazi.

3. Pulmonologiya asoslari. Davolash ishi yo‘nalishi talabalari uchun darslik. Samarqand: Samarqand davlat tibbiyot universiteti elektron kutubxonasi.

4. Qo‘ldoshev F. Z., Xasanov F. Sh. O‘pka absessi va gangrenasi. Ilmiy maqola. Yangi O‘zbekiston ilmiy jurnali, 2024.

5. Karimov Sh. I. va hammualliflar. Xirurgik kasalliklar. Tibbiyot oliy o‘quv yurtlari talabalari uchun darslik. Toshkent: Tibbiyot nashriyoti.

6. O‘zbekiston Respublikasi Sog‘liqni saqlash vazirligi. Ichki kasalliklar va pulmonologiya bo‘yicha o‘quv-uslubiy materiallar. Toshkent.

7. Chatha N., Fortin D., Bosma K. J. Management of necrotizing pneumonia and pulmonary gangrene: a case series and review of the literature. Canadian Respiratory Journal, 2014.

8. Kapania E. M., et al. Necrotizing Pneumonia: A Practical Guide for the Clinician. Journal of Clinical Medicine and Pulmonary Practice, 2024.

9. Sabbula B. R., et al. Lung Abscess. StatPearls Publishing. Treasure Island, 2024.

10. Kuhajda I., et al. Lung abscess: etiology, diagnostic and treatment options. Annals of Translational Medicine, 2015.

11. MSD Manual Professional Edition. Lung Abscess. Pulmonary Disorders Section, updated medical review.

12. Ali K. Role of surgery in the management of necrotizing pneumonia. Journal of Visualized Surgery, 2019.

13. Jameson J. L., Fauci A. S., Kasper D. L., Hauser S. L., Longo D. L., Loscalzo J. Harrison’s Principles of Internal Medicine. New York: McGraw-Hill Education.

14. Broaddus V. C., Mason R. J., Ernst J. D., King T. E., Lazarus S. C., Murray J. F., Nadel J. A. Murray and Nadel’s Textbook of Respiratory Medicine. Philadelphia: Elsevier.

15. Grippi M. A., Elias J. A., Fishman J. A., Kotloff R. M., Pack A. I., Senior R. M. Fishman’s Pulmonary Diseases and Disorders. New York: McGraw-Hill Education.

16. Bennett J. E., Dolin R., Blaser M. J. Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. Philadelphia: Elsevier.

17. World Health Organization. Clinical management of severe acute respiratory infection: practical guidance for health-care workers. Geneva: WHO.

18. National Institute for Health and Care Excellence. Pneumonia in adults: diagnosis and management. London: NICE.

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Copyright (c) 2026 Afruza Farxodova, Bexruz Kibriyev

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